US Patent

US7786133 — Chemically modified small molecules

Composition of Matter · Assigned to Nektar Therapeutics · Expires 2028-09-16 · 2y remaining

Vulnerability score 22/100 Ironclad — strong claim type, well-established, deep family

What this patent protects

This patent protects chemically modified small molecules, specifically those with a covalently attached water-soluble oligomer, as a drug substance or product.

USPTO Abstract

The invention provides small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer obtained from a monodisperse or bimodal water-soluble oligomer composition. A conjugate of the invention, when administered by any of a number of administration routes, exhibits a reduced biological membrane crossing rate as compared to the biological membrane crossing rate of the small molecule drug not attached to the water-soluble oligomer.

Drugs covered by this patent

Patent Metadata

Patent number
US7786133
Jurisdiction
US
Classification
Composition of Matter
Expires
2028-09-16
Drug substance claim
Yes
Drug product claim
Yes
Assignee
Nektar Therapeutics
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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