US Patent

US7598257 — Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors

Method of Use · Assigned to Incyte Corp · Expires 2027-12-24 · 2y remaining

Vulnerability score 63/100 Moderate — design-around opportunities exist

What this patent protects

This patent protects a class of compounds that inhibit Janus kinases and are useful in treating various diseases, including immune-related diseases and cancer.

USPTO Abstract

The present invention provides heteroaryl substituted pyrrolo[2,3-b]pyridines and heteroaryl substituted pyrrolo[2,3-b]pyrimidines that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-3228 ruxolitinib-phosphate
U-3227 ruxolitinib-phosphate
U-3227 ruxolitinib-phosphate
U-3228 ruxolitinib-phosphate
U-3228 ruxolitinib-phosphate

Patent Metadata

Patent number
US7598257
Jurisdiction
US
Classification
Method of Use
Expires
2027-12-24
Drug substance claim
Yes
Drug product claim
Yes
Assignee
Incyte Corp
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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