US Patent
US7378423 — Pyrimidine compound and medical use thereof
Composition of Matter · Assigned to Japan Tobacco Inc · Expires 2027-05-29 · 1y remaining
Vulnerability score
22/100
Ironclad — strong claim type, well-established, deep family
What this patent protects
This patent protects a pyrimidine compound represented by formula [I] and its use in treating undesirable cell proliferation, particularly cancer.
USPTO Abstract
The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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