US Patent

US6967208 — Lactam-containing compounds and derivatives thereof as factor Xa inhibitors

Method of Use · Assigned to Bristol Myers Squibb Pharma Co · Expires 2026-11-21 · 1y remaining

Vulnerability score 93/100 Vulnerable — likely target for IPR or design-around

What this patent protects

This patent protects lactam-containing compounds and their derivatives that inhibit factor Xa, a type of enzyme.

USPTO Abstract

The present application describes lactam-containing compounds and derivatives thereof of Formula I: or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-4179 Eliquis
U-4180 Eliquis
U-1501 Eliquis
U-1301 Eliquis

Patent Metadata

Patent number
US6967208
Jurisdiction
US
Classification
Method of Use
Expires
2026-11-21
Drug substance claim
Yes
Drug product claim
Yes
Assignee
Bristol Myers Squibb Pharma Co
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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