US Patent

US12544383 — Methods of treating migraines with a combination of a meloxicam and a rizatriptan

Method of Use · Assigned to Axsome Therapeutics Inc · Expires 2045-03-10 · 19y remaining

Vulnerability score 63/100 Moderate — design-around opportunities exist

What this patent protects

This patent protects methods of treating migraines by administering a combination of meloxicam and rizatriptan to a human being.

USPTO Abstract

Disclosed herein are compositions comprising an NSAID such as meloxicam and/or rizatriptan in combination with a cyclodextrin and/or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability or pharmacokinetics of meloxicam and/or rizatriptan for the treatment of pain such as migraine, arthritis, and other conditions. Also disclosed herein are methods of treating pain, such as migraine, comprising administering meloxicam and rizatriptan to a human being suffering from pain, such as migraine. For migraine, these methods may be particularly useful when the meloxicam and rizatriptan are administered while the human being is suffering from an acute attack of migraine pain or migraine aura.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-1719 Mobic

Patent Metadata

Patent number
US12544383
Jurisdiction
US
Classification
Method of Use
Expires
2045-03-10
Drug substance claim
No
Drug product claim
No
Assignee
Axsome Therapeutics Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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