US12433890 — Method of treating SCLC and managing neutropenia
Method of Use · Assigned to Pharmamar SA · Expires 2040-05-29 · 14y remaining
What this patent protects
This patent protects methods for treating small cell lung cancer (SCLC) patients using lurbinectedin, either alone or in combination with other anticancer drugs.
USPTO Abstract
Provided are methods for the treatment of SCLC patients by administering therapeutic amounts of lurbinectedin by intravenous infusion. Also provided are methods of treating cancer by administering lurbinectedin in combination with other anticancer drugs, in particular topoisomerase inhibitors. The invention further relates to the administration of lurbinectedin in combination with anti-emetic agents for effective control of symptoms related to nausea and vomiting, reduced lurbinectedin dosages to achieve a safer administration and an increase in the number of treatment cycles. Stable lyophilized formulations of lurbinectedin are also provided.
Drugs covered by this patent
- Zepzelca (LURBINECTEDIN) · Jazz Pharmaceuticals
FDA Patent Use Codes
When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.
| Code | Description | Drug |
|---|---|---|
U-4305 |
— | Zepzelca |
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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