US Patent

US12239689 — Controlled-release CNP agonists with low initial NPR-B activity

Method of Use · Assigned to Ascendis Pharma Growth Disorders AS · Expires 2037-01-05 · 11y remaining

Vulnerability score 75/100 Vulnerable — likely target for IPR or design-around

What this patent protects

This patent protects a controlled-release version of a CNP agonist that has specific properties and is used in pharmaceutical compositions for treatment.

USPTO Abstract

The present invention relates to a controlled-release CNP agonist from which CNP agonist is released with a release half-life of at least 6 hours under physiological conditions and which controlled-release CNP agonist has an EC 50 that is at least 20-fold higher than the EC 50 of the corresponding free CNP agonist and which released CNP agonist has an EC 50 that is at most 3-fold higher than the EC 50 of the corresponding free CNP agonist; to pharmaceutical compositions comprising said controlled-release CNP agonist; their use; and to methods of treatment.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-4425 —
U-4425 —
U-4425 —

Patent Metadata

Patent number
US12239689
Jurisdiction
US
Classification
Method of Use
Expires
2037-01-05
Drug substance claim
No
Drug product claim
No
Assignee
Ascendis Pharma Growth Disorders AS
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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