US12233035 — Method of treating cardiovascular events using colchicine concurrently with an antiplatelet agent and statin
Method of Use · Assigned to Murray and Poole Enterprises Ltd · Expires 2033-11-01 · 7y remaining
What this patent protects
This patent protects a method of reducing cardiovascular event risk in patients with a history of diabetes and certain cardiovascular conditions by administering a daily oral dose of colchicine.
USPTO Abstract
A method for reducing a composite endpoint risk of myocardial infarction (MI), stroke, coronary revascularization, unstable angina requiring hospitalization, cardiac arrest, and cardiovascular death in a subject including administering, orally once per day to the subject, a composition comprising about 0.5 total mg of (i) colchicine, (ii) a pharmaceutically acceptable salt of (i), or any combination of (i) and (ii), wherein the patient has at least one history of diabetes, a past myocardial infarction, an unstable angina, a coronary bypass surgery, and a coronary angioplasty; wherein the patient is also administered a daily dose of statin therapy; and wherein the composite endpoint risk in the subject is reduced relative to a dosing regimen where the patient receives standard secondary prevention therapy of a statin.
Drugs covered by this patent
- Colcrys (COLCHICINE) · Scilex Pharms
FDA Patent Use Codes
When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.
| Code | Description | Drug |
|---|---|---|
U-4132 |
— | Colcrys |
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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