US Patent
US12187739 — Diaryl macrocycle polymorph
Formulation · Assigned to Turning Point Therapeutics Inc · Expires 2036-07-05 · 10y remaining
Vulnerability score
55/100
Moderate — design-around opportunities exist
What this patent protects
This patent protects polymorphs of a specific compound useful in treating diseases like cancer in mammals, including humans.
USPTO Abstract
This disclosure relates to polymorphs of (7S,13R)-11-fluoro-7,13-dimethyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one that are useful in the treatment of disease, such as cancer, in mammals. This disclosure also relates to compositions including such polymorphs, and to methods of using such compositions in the treatment of diseases, such as cancer, in mammals, especially in humans.
Drugs covered by this patent
- Augtyro (REPOTRECTINIB) · Bristol
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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