US Patent
US12042504 — Injectable fosaprepitant composition
Formulation · Assigned to Spes Pharmaceuticals Inc · Expires 2039-01-11 · 13y remaining
Vulnerability score
55/100
Moderate — design-around opportunities exist
What this patent protects
This patent protects stable compositions of fosaprepitant or a pharmaceutically acceptable salt thereof, lacking polysorbate 80, and containing dual functional excipients.
USPTO Abstract
The present application and its embodiments teach stable compositions of fosaprepitant or a pharmaceutically acceptable salt thereof with such compositions lacking polysorbate 80 and containing dual functional excipients of hydrolysis inhibition and solubility enhancement. Further described are methods of preparation of such compositions. Among other advantages of contemplated compositions, fosaprepitant hydrolysis degradation is kept low and the compositions maintain physically and chemically stable for prolonged period.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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