US Patent

US12011506 — Combination and uses and treatments thereof

Formulation · Assigned to Janssen Sciences Ireland ULC · Expires 2038-09-05 · 12y remaining

Vulnerability score 55/100 Moderate — design-around opportunities exist

What this patent protects

This patent protects methods for treating or preventing HIV-1 or HIV-2 in virologically suppressed patients by switching their treatment regimen to a combination of dolutegravir and rilpivirine.

USPTO Abstract

Methods are provided for treating or preventing human immunodeficiency virus-1 (HIV-1) or human immunodeficiency virus-2 (HIV-2) in a virologically suppressed patient in need thereof comprising switching the patient from an antiretroviral treatment regimen comprising at least three antiretroviral agents to a treatment regimen comprising only two antiretroviral agents. In one aspect the two treatment regimen consists of dolutegravir, rilpivirine and at least one pharmaceutically acceptable excipient, diluent or carrier. In another aspect of the invention, there is provided a multilayer tablet comprising dolutegravir or a pharmaceutically acceptable salt thereof and rilpivirine or a pharmaceutically acceptable salt thereof.

Drugs covered by this patent

Patent Metadata

Patent number
US12011506
Jurisdiction
US
Classification
Formulation
Expires
2038-09-05
Drug substance claim
No
Drug product claim
Yes
Assignee
Janssen Sciences Ireland ULC
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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