US11874283 — Method and compositions for the treatment and detection of endothelin-1 related kidney diseases
Method of Use · Assigned to Morehouse School of Medicine Inc · Expires 2032-02-18 · 6y remaining
What this patent protects
This patent protects methods and compositions for treating HIV-associated nephropathy and/or focal segmental glomerulosclerosis using endothelin-1 antagonists.
USPTO Abstract
The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
Drugs covered by this patent
FDA Patent Use Codes
When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.
| Code | Description | Drug |
|---|---|---|
U-3980 |
— | atrasentan-hydrochloride |
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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