US Patent
US11498913 — Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors
Formulation · Assigned to Forma Therapeutics Inc · Expires 2035-09-18 · 9y remaining
Vulnerability score
50/100
Moderate — design-around opportunities exist
What this patent protects
This patent protects a class of compounds that inhibit mutant isocitrate dehydrogenase proteins, useful in treating cell-proliferation disorders and cancers.
USPTO Abstract
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: where A, U, W 1 , W 2 , W 3 , R 1 -R 6 , and R 9 are described herein.
Drugs covered by this patent
- Rezlidhia (OLUTASIDENIB) · Rigel Pharms
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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