US Patent

US11458134 — 1-[2-(2,4-dimeihylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment

Method of Use · Assigned to H Lundbeck AS · Expires 2027-06-15 · 1y remaining

Vulnerability score 83/100 Vulnerable — likely target for IPR or design-around

What this patent protects

The patent US 11458134 protects the use of 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine for treating cognitive impairment, especially in depressed patients.

USPTO Abstract

1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.

Drugs covered by this patent

vortioxetine-hydrobromide (VORTIOXETINE HYDROBROMIDE)

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

Code	Description	Drug
`U-3463`	—	vortioxetine-hydrobromide
`U-3463`	—	vortioxetine-hydrobromide
`U-3463`	—	vortioxetine-hydrobromide
`U-3463`	—	vortioxetine-hydrobromide

Patent Metadata

Patent number: US11458134
Jurisdiction: US
Classification: Method of Use
Expires: 2027-06-15
Drug substance claim: No
Drug product claim: Yes
Assignee: H Lundbeck AS
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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