US Patent

US11452720 — Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde

Method of Use · Assigned to Global Blood Therapeutics Inc · Expires 2035-02-06 · 9y remaining

Vulnerability score 53/100 Moderate — design-around opportunities exist

What this patent protects

This patent protects crystalline forms of the free base of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde.

USPTO Abstract

Disclosed are crystalline free base ansolvate forms of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde (or Compound 1), such as the free base Form I, Form II and Material N. Also disclosed are crystalline free base solvates of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde (or Compound 1).

Drugs covered by this patent

Oxbryta (voxelotor) · Global Blood Theraps

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

Code	Description	Drug
`U-3459`	—	Oxbryta
`U-3459`	—	Oxbryta
`U-3459`	—	Oxbryta

Patent Metadata

Patent number: US11452720
Jurisdiction: US
Classification: Method of Use
Expires: 2035-02-06
Drug substance claim: No
Drug product claim: No
Assignee: Global Blood Therapeutics Inc
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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