US Patent

US11045474 — Antiviral JAK inhibitors useful in treating or preventing coronaviridae infections

Method of Use · Assigned to Emory University · Expires 2032-11-30 · 7y remaining

Vulnerability score 70/100 Vulnerable — likely target for IPR or design-around

What this patent protects

This patent discloses compounds and methods for treating or preventing HIV infection using JAK inhibitors, including combinations with other antiretroviral compounds.

USPTO Abstract

Compounds, compositions, and methods of treatment and prevention of HIV infection are disclosed. The compounds are pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidine JAK inhibitors. Combinations of these JAK inhibitors and additional antiretroviral compounds, such as NRTI, NNRTI, integrase inhibitors, entry inhibitors, protease inhibitors, and the like, are also disclosed. In one embodiment, the combinations include a combination of adenine, cytosine, thymidine, and guanine nucleoside antiviral agents, optionally in further combination with at least one additional antiviral agent that works via a different mechanism than a nucleoside analog. This combination has the potential to eliminate the presence of HIV in an infected patient.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-3372 — Olumiant
U-3372 — Olumiant
U-3372 — Olumiant

Patent Metadata

Patent number
US11045474
Jurisdiction
US
Classification
Method of Use
Expires
2032-11-30
Drug substance claim
No
Drug product claim
No
Assignee
Emory University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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