US Patent

US10988436 — Crystalline form of triethylenetetramine tetrahydrochloride and its pharmaceutical use

Composition of Matter · Assigned to Orphalan SA · Expires 2039-05-03 · 13y remaining

Vulnerability score 12/100 Ironclad — strong claim type, well-established, deep family

What this patent protects

This patent protects a new crystalline form of triethylenetetramine tetrahydrochloride with improved room temperature stability for use in treating Wilson's disease.

USPTO Abstract

The present invention describes a new crystalline form of triethylenetetramine tetrachloride which has improved room temperature stability over known forms and over the dichloride salt. The new crystalline form is characterised by having peaks in an XRPD spectrum at 22.9, 25.4, 25.8, 26.6, 34.6 and 35.3±0.1°2θ and Raman shifts 943, 1173, 1527 and 1612±5 cm−1. The crystalline form of triethylenetetramine tetrachloride is useful in the treatment of Wilson's disease.

Drugs covered by this patent

Patent Metadata

Patent number
US10988436
Jurisdiction
US
Classification
Composition of Matter
Expires
2039-05-03
Drug substance claim
Yes
Drug product claim
No
Assignee
Orphalan SA
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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