US10952997 — Methods for the administration of certain VMAT2 inhibitors
Method of Use · Assigned to Neurocrine Biosciences Inc · Expires 2037-10-10 · 11y remaining
What this patent protects
This patent protects methods of administering valbenazine tosylate to patients who are also taking a strong CYP3A4 inhibitor.
USPTO Abstract
Provided are methods of administering a vesicular monoamine transport 2 (VMAT2) inhibitor chosen from valbenazine and (+)-a-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol, or a pharmaceutically acceptable salt and/or isotopic variant thereof, to a patient in need thereof wherein the patient is also being administered a strong cytochrome P450 3A4 (CYP3A4) inhibitor.
Drugs covered by this patent
FDA Patent Use Codes
When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.
| Code | Description | Drug |
|---|---|---|
U-1995 |
— | valbenazine-tosylate |
U-1995 |
— | valbenazine-tosylate |
U-1995 |
— | valbenazine-tosylate |
U-1995 |
— | valbenazine-tosylate |
U-1995 |
— | valbenazine-tosylate |
U-1995 |
— | valbenazine-tosylate |
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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