US Patent

US10947183 — Fenfluramine compositions and methods of preparing the same

Composition of Matter · Assigned to Zogenix International Ltd · Expires 2036-12-20 · 11y remaining

Vulnerability score 4/100 Ironclad — strong claim type, well-established, deep family

What this patent protects

This patent protects methods for preparing fenfluramine compositions, including a method of reductively aminating 1-(3-(trifluoromethyl)phenyl)propan-2-one with ethylamine.

USPTO Abstract

(c) reductively aminating the 1-(3-(trifluoromethyl)phenyl)propan-2-one composition with ethylamine using a borohydride reducing agent to produce a fenfluramine composition. Also provided are compositions and pharmaceutical ingredients prepared according to the subject methods including a pharmaceutically acceptable salt of fenfluramine and having less than 0.2% by weight in total of trifluoromethyl regioisomers.

Drugs covered by this patent

fenfluramine-hydrochloride (FENFLURAMINE HYDROCHLORIDE)

Patent Metadata

Patent number: US10947183
Jurisdiction: US
Classification: Composition of Matter
Expires: 2036-12-20
Drug substance claim: Yes
Drug product claim: Yes
Assignee: Zogenix International Ltd
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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