US Patent

US10888547 — Amorphous and a crystalline form of genz 112638 hemitartrate as inhibitor of glucosylceramide synthase

Method of Use · Assigned to Genzyme Corp · Expires 2031-01-31 · 5y remaining

Vulnerability score 68/100 Moderate — design-around opportunities exist

What this patent protects

This patent discloses methods of producing crystalline genz 112638 hemitartrate and using it to inhibit glucosylceramide synthase or lower glycosphingolipid concentrations.

USPTO Abstract

The hemitartrate salt of a compound represented by the following structural formula: (Formula I Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-3042 eliglustat-tartrate

Patent Metadata

Patent number
US10888547
Jurisdiction
US
Classification
Method of Use
Expires
2031-01-31
Drug substance claim
No
Drug product claim
No
Assignee
Genzyme Corp
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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