US Patent

US10821113 — Salt form of a human histone methyltransferase EZH2 inhibitor

Composition of Matter · Assigned to Eisai R&D Management Co Ltd · Expires 2033-04-11 · 7y remaining

Vulnerability score 4/100 Ironclad — strong claim type, well-established, deep family

What this patent protects

Provided herein is N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl (tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4â²-(morpholinomethyl)-[1,1â²-biphenyl]-3-carboxamide hydrobromide. Also provided herein is a particular polymorph form of this compound.

USPTO Abstract

Provided herein is N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl (tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4â²-(morpholinomethyl)-[1,1â²-biphenyl]-3-carboxamide hydrobromide. Also provided herein is a particular polymorph form of this compound.

Drugs covered by this patent

tazemetostat-hydrobromide (TAZEMETOSTAT HYDROBROMIDE)

Patent Metadata

Patent number: US10821113
Jurisdiction: US
Classification: Composition of Matter
Expires: 2033-04-11
Drug substance claim: Yes
Drug product claim: Yes
Assignee: Eisai R&D Management Co Ltd
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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