US Patent
US10383853 — Carboxamide derivative and its diastereomers in stable crystalline form
Composition of Matter · Assigned to Orion Oyj · Expires 2036-01-28 · 10y remaining
Vulnerability score
0/100
Ironclad — strong claim type, well-established, deep family
What this patent protects
This patent protects stable crystalline forms of a specific carboxamide derivative and its diastereomers, which are potent androgen receptor modulators.
USPTO Abstract
The present disclosure relates to solid crystalline forms of Nâ((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)-propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide (I) and the diastereomers thereof, and to methods for preparing such crystalline forms. Compound (I) and the diastereomers thereof are potent androgen receptor (AR) modulators useful as a medicament.
Drugs covered by this patent
- Nubeqa (darolutamide) · Bayer
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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