US Patent
US10300041 — Liquid oral simvastatin compositions
Formulation · Assigned to Rosemont Pharmaceuticals Ltd · Expires 2027-04-26 · 1y remaining
Vulnerability score
60/100
Moderate — design-around opportunities exist
What this patent protects
This patent protects a liquid oral simvastatin composition with specific particle size and concentration requirements.
USPTO Abstract
Aqueous suspensions for oral administration are disclosed that include simvastatin having a d 90 of simvastatin particles of less than about 100 μm as the active agent. The aqueous suspension also includes simvastatin as about 20 mg to about 80 mg per 5 ml of the aqueous suspension, a suspending agent as about 20 mg to about 50 mg of the aqueous suspension, a wetting agent, an antimicrobial preservative, an antifoaming agent, water, and a buffering system providing the aqueous suspension with a pH of about 6.4 to about 7. Methods of making such a suspension and methods of treatments in orally administering the same are also disclosed.
Drugs covered by this patent
- Zocor (simvastatin) · Merck & Co.
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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