US Patent

US10231965 — Molecules for administration to ROS1 mutant cancer cells

Method of Use · Assigned to Nerviano Medical Sciences SRL · Expires 2035-02-17 · 9y remaining

Vulnerability score 62/100 Moderate — design-around opportunities exist

What this patent protects

This patent discloses substituted indazole derivatives and their pharmaceutical compositions for use in treating diseases associated with deregulated protein kinase activity, such as cancer.

USPTO Abstract

Substituted indazole derivatives of formula (I) or formula 2.(I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer.

Drugs covered by this patent

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

CodeDescriptionDrug
U-2618 Rozlytrek
U-2618 Rozlytrek

Patent Metadata

Patent number
US10231965
Jurisdiction
US
Classification
Method of Use
Expires
2035-02-17
Drug substance claim
No
Drug product claim
No
Assignee
Nerviano Medical Sciences SRL
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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