US Patent

US10166181 — Slow release pharmaceutical composition made of microgranules

Formulation · Assigned to Debiopharm Research and Manufacturing SA · Expires 2029-06-30 · 3y remaining

Vulnerability score 48/100 Strong — defensible against typical IPR challenges

What this patent protects

This patent protects a slow-release pharmaceutical composition made of microgranules containing a water-insoluble peptide salt of an active substance.

USPTO Abstract

Pharmaceutical composition made of microparticles for the slow release of an active substance at least during a period covering the 6th month after injection of said composition, said composition comprising a group of microparticles made of a copolymer of the PLGA type which incorporate an active substance in the form of a water insoluble peptide salt; said copolymer furthermore comprising at least 75% of lactic acid and an inherent viscosity between 0.1 and 0.9 dl/g, as measured in chloroform at 25° C. and at a polymer concentration of 0.5 g/dL; said microparticles furthermore having a size distribution defined as follows: —D (v,0.1) is between 10 and 30 micrometers, —D (v,0.5) is between 30 and 70 micrometers, —D (v,0.9) is between 50 and 1 10 micrometers.

Drugs covered by this patent

Patent Metadata

Patent number
US10166181
Jurisdiction
US
Classification
Formulation
Expires
2029-06-30
Drug substance claim
No
Drug product claim
Yes
Assignee
Debiopharm Research and Manufacturing SA
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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