US Patent

US10125369 — PCSK9 iRNA compositions and methods of use thereof

Method of Use · Assigned to Alnylam Pharmaceuticals Inc · Expires 2034-08-18 · 8y remaining

Vulnerability score 70/100 Vulnerable — likely target for IPR or design-around

What this patent protects

This patent protects RNAi agents targeting the PCSK9 gene and methods of using them to treat subjects with lipid disorders.

USPTO Abstract

The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the PCSK9 gene, and methods of using such RNAi agents to inhibit expression of PCSK9 and methods of treating subjects having a lipid disorder, such as a hyperlipidemia.

Drugs covered by this patent

inclisiran-sodium (INCLISIRAN SODIUM)

FDA Patent Use Codes

When a patent is method-of-use, FDA lists it once per applicable indication ("U-code"). Each U-code carves out a specific therapeutic use that generic filers must either license or design around.

Code	Description	Drug
`U-4413`	—	inclisiran-sodium

Patent Metadata

Patent number: US10125369
Jurisdiction: US
Classification: Method of Use
Expires: 2034-08-18
Drug substance claim: Yes
Drug product claim: Yes
Assignee: Alnylam Pharmaceuticals Inc
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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