GB2586026A — Use of cannabidol in the treatment of Dravet syndrome

USPTO Abstract

Cannabidiol (CBD) is disclosed for use in the treatment of disease modification in Dravet syndrome, a treatment-resistant epilepsy. Preferably, CBD is used to improve neonatal welfare, survival and co-morbidities in patients with Dravet syndrome. Preferably the CBD used is in the form of a botanically derived purified CBD which comprises greater than or equal to 98% (w/w) CBD and less than or equal to 2% (w/w) of other cannabinoids. The other cannabinoids present are THC at a concentration of less than or equal to 0.1% (w/w); CBD-C1 at a concentration of less than or equal to 0.15% (w/w); CBDV at a concentration of less than or equal to 0.8% (w/w); and CBD-C4 at a concentration of less than or equal to 0.4% (w/w). The botanically derived purified CBD preferably also comprises a mixture of both trans-THC and cis-THC. Alternatively, a synthetically produced CBD is used.