GB Patent

GB2291422A — 4-phenyl-pyrido[2,3-b]pyrazin-4-ones

Assigned to Fujisawa Pharmaceutical Co Ltd · Expires 1996-01-24 · 30y expired

What this patent protects

Pyridopyrazine derivatives of the following formula: <IMAGE> wherein R<1> is a lower alkyl, carboxy or protected carboxy, and R<2> is aryl which may have protected amino, and pharmaceutically acceptable salts thereof. A process for preparing such co…

USPTO Abstract

Pyridopyrazine derivatives of the following formula: <IMAGE> wherein R<1> is a lower alkyl, carboxy or protected carboxy, and R<2> is aryl which may have protected amino, and pharmaceutically acceptable salts thereof. A process for preparing such compounds is also described. These compounds possess inhibitory activity against both phosphodiesterase IV (PDE-IV) and the production of tumour necrosis factor (TNF), and can therefore be used for the prophylactic and therapeutic treatment of PDE-IV and TNF mediated diseases, such as chronic inflammatory diseases, autoimmune diseases and sepsis-induced organ injury.

Drugs covered by this patent

Patent Metadata

Patent number
GB2291422A
Jurisdiction
GB
Classification
—
Expires
1996-01-24
Drug substance claim
No
Drug product claim
No
Assignee
Fujisawa Pharmaceutical Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

Track this patent

Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.