GB2266529A — Tetrahydroisoquinoline derivatives
Assigned to Organon Pharma UK Ltd · Expires 1993-11-03 · 33y expired
What this patent protects
Compounds of formula (I), and salts and prodrugs thereof <IMAGE> wherein: R<1> is H, C1-6alkyl or optionally substituted phenyl; R<2> is H, C1-6alkyl, COR<7>, COOR<7>, CONHR<7> or optionally substituted phenylC1-4alkyl; R<7> is C1-6al…
USPTO Abstract
Compounds of formula (I), and salts and prodrugs thereof <IMAGE> wherein: R<1> is H, C1-6alkyl or optionally substituted phenyl; R<2> is H, C1-6alkyl, COR<7>, COOR<7>, CONHR<7> or optionally substituted phenylC1-4alkyl; R<7> is C1-6alkyl or optionally substituted phenyl; R<3> is optionally substituted phenyl; each R<4> is C1-6alkyl, C1-6alkoxy, halo or trifluoromethyl; R<5> is H or C1-6alkyl; R<6> is H, C1-6alkyl or optionally substituted phenyl; n is 0, 1, 2, 3 or 4; X is CH2 or C=0; Y is O, S, CH2 or NR<10>; where R<10> is H, C1-6alkyl or COR<5>; or X and Y together represent CH=CH; with the proviso that X is not C=O when Y is CH2; are tachykinin receptor antagonists useful in therapy.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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