GB1459488A — Piperazinedione derivatives
Assigned to John Wyeth and Brother Ltd · Expires 1976-12-22 · 49y expired
What this patent protects
1459488 Dipeptide derivative JOHN WYETH & BRO Ltd 19 March 1975 [19 March 1974] 12051/74 Heading C3H [Also in Division C2] N<SP>α</SP> - glycyl - N<SP>#</SP> - carbobenzoxy - L - lysine methyl ester is prepared by esterification of N<SP>α</SP&…
USPTO Abstract
1459488 Dipeptide derivative JOHN WYETH & BRO Ltd 19 March 1975 [19 March 1974] 12051/74 Heading C3H [Also in Division C2] N<SP>α</SP> - glycyl - N<SP>#</SP> - carbobenzoxy - L - lysine methyl ester is prepared by esterification of N<SP>α</SP> - glycyl - N<SP>#</SP> - carbobenzoxy - L - lysine with methanol in the presence of boron trifluoride etherate with heating at 80 C. for 25 hours. The ester is isolated as its hydrochloride (Example 1).
Drugs covered by this patent
- Remodulin (TREPROSTINIL) · United Therap
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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