GB1351761A — Substituted p-menthane carboxamides and compositions containing them

USPTO Abstract

1351761 Comestible products WILKINSON SWORD Ltd 26 Jan 1972 [4 Feb 1971] 3928/71 Heading A2B [Also in Divisions A4 A5 C2 C4 C5 C6] A comestible composition comprises an edible base, a flavourant or colourant and one or more novel p-methane-3-carboxamide of the formula: wherein R' is H or C 1-25 aliphatic radical, R" is hydroxy or C 1-25 aliphatic radical, with the proviso that when R' is HR" may also be substituted phenyl, optionally substituted phenalkyl optionally substituted naphthyl or pyridyl, or R' and R" together with the nitrogen atom to which they are attached form a heterocyclic ring optionally containing further hetero atoms. The compounds may be added to boiled sweets, mint sweets, chewing gum and ice cream. The compounds are capable of stimulating the cold receptors of the nervous system of the human body.