GB1198301A — Perfluoroalkylsulfonamides

USPTO Abstract

1,198,301. Sulphonamide compositions. MINNESOTA MINING & MFG. CO. 20 Oct., 1967 [21 Oct., 1966], No. 47928/67. Headings A5B and A5E. [Also in Division C2] Anti-inflammatory, analgesic, antipyretic and antifibrinolytic, and antimicrobial, e.g. antiparasitic, antibacterial and antifugal, pesticidal, e.g. insecticidal and nematocidal and plant growth regulative penfluoralkylsulphonamides are of the general formula: R f SO 2 NR 2 R 3 ; wherein R f signifies a C 1-8 perfluoroalkyl group, R 2 signifies a hydrogen atom, a C 1-6 alkyl group or a cation (includes ammonium and substituted ammonium cations) and R 3 signifies a heteroatom containing organic group (the heteroatom can occur in a heterocyclic ring or in the form of an acylic grouping, e.g. in substituents of rings or in aliphatic groups) which is bonded to the nitrogen atom in the foregoing formula through an aromatic ring therein (includes aromatic heterocyclic). Pharmaceutical preparations in the form of aqueous solutions or as suspensions in an aqueous or non-aqueous suspending agent, e.g. gum acacia and containing the above sulphonamides can be administered orally or injected subcutaneously or intramuscularly. The sulphonamides may also 'be administered in the form of capsules, tablets, powders, sterile solutions of water or other solvents or other dosage forms in association with conventional diluents and adjuvants as well as other tableting aids and fillers. For application to plants the sulphonamides can be finely divided in an aqueous suspension and other agents may also be incorporated therein. Dry powders can also be utilized.