EP4698205A1 — Pharmaceutical formulations for longevity in mammals

USPTO Abstract

Disclosed herein are extended release octreotide dosage forms containing octreotide, or a pharmaceutically acceptable salt thereof, and a biodegradable polymer microsphere. Disclosed herein are also kits of formulation including a first vial containing a microsphere loaded with octreotide, or a pharmaceutically acceptable salt thereof, and a biodegradable polymer and a second vial including a pharmaceutically acceptable diluent. Also, disclosed herein are methods of preventing or reducing an age-related decline in quality of life or an age-related increase in frailty in a mammal by administering to the mammal a therapeutically effective amount of the extended release octreotide dosage form or providing the kit of formulation to the mammal.