EP Patent

EP4689660A1 — Kat6a as a predictive biomarker for treatment with a kat6a inhibitor and methods of treatment thereof

Assigned to CTXT Pty Ltd · Expires 2026-02-11 · 0y expired

What this patent protects

This invention relates to a method of selecting a subject having a cancer for treatment, comprising: i) determining a KAT6A level from a biological sample of the cancer from the subject; ii) selecting the subject for treatment and iii) administering to the selected subject an amo…

USPTO Abstract

This invention relates to a method of selecting a subject having a cancer for treatment, comprising: i) determining a KAT6A level from a biological sample of the cancer from the subject; ii) selecting the subject for treatment and iii) administering to the selected subject an amount of with one of: a) a lysine acetyltransferase 6A (KAT6A) inhibitor; b) a lysine acetyltransferase 6A (KAT6A) inhibitor and a cyclin-dependent kinase 4 (CDK4) inhibitor; c) a lysine acetyltransferase 6A (KAT6A) inhibitor and an antiestrogen; and d) a lysine acetyltransferase 6A (KAT6A) inhibitor, a cyclin-dependent kinase 4 (CDK4) inhibitor, and an antiestrogen, based on the KAT6A level, wherein the KAT6A level is determined to be high.

Drugs covered by this patent

Patent Metadata

Patent number
EP4689660A1
Jurisdiction
EP
Classification
Expires
2026-02-11
Drug substance claim
No
Drug product claim
No
Assignee
CTXT Pty Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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