EP4687918A2 — Pharmacological therapy for mitochondrial dna depletion deletions syndrome involving mutations in the guk1 gene
Assigned to Columbia University in the City of New York · Expires 2026-02-11 · 0y expired
What this patent protects
Compositions and methods relating to a pharmacological therapy for a human genetic disease, specifically mitochondrial DNA depletion-deletions syndromes, and more specifically, those related to mutations in the GUK1 gene. The pharmacological therapy involves the administration of…
USPTO Abstract
Compositions and methods relating to a pharmacological therapy for a human genetic disease, specifically mitochondrial DNA depletion-deletions syndromes, and more specifically, those related to mutations in the GUK1 gene. The pharmacological therapy involves the administration of deoxyguanosine (dG), a purine nucleoside phosphorylase (PNP) inhibitor, including but not limited to forodesine, or both.
Drugs covered by this patent
- Kygevvi (DOXECITINE) · Ucb Inc
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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