EP4684777A1 — A fixed-dose pharmaceutical composition comprising (2s)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid and (6r,12ar)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino{1',2:1,6]pyrido[3,4-b]indole-1,4-dione

USPTO Abstract

The present invention relates to a fixed-dose pharmaceutical composition comprising (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid or its pharmaceutically acceptable salt, ester, solvate, polymorph, enantiomer or mixture thereof and (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]in dole-1,4-dione or its pharmaceutically acceptable salt, ester, solvate, polymorph, enantiomer or mixture thereof, wherein the composition is further comprising one or more pharmaceutically acceptable excipients, and also a process for the preparation thereof.