EP4629998A1 — Ready-to-use injectable formulations of lurbinectedin

USPTO Abstract

The present invention relates to ready to use injectable formulation of Lurbinectedin. The invention makes it possible to administer Lurbinectedin without the need for reconstitution. The liquid formulation comprises Lurbinectedin and/ or its pharmaceutically acceptable salts and pharmaceutically acceptable excipients for parenteral administration. The present invention provides a polymer based dual or multi-chamber bag for the intravenous administration of Lurbinectedin wherein one chamber contains Lurbinectedin ready-to-use solution, and another chamber contains diluent or a multi-diluent system for parenteral administration. The present invention provides a polymer based dual or multi-chamber bag for the intravenous administration of Lurbinectedin wherein it contains Lurbinectedin ready- to-administer for parenteral administration.