EP4626866A1 — Novel trilaciclib intermediates, method of preparation and use thereof

USPTO Abstract

Aspects of the present disclosure provide novel intermediates that may be used for synthesis of Trilaciclib, pharmaceutically acceptable salts or derivatives thereof. Aspects of the present disclosure also relate to a method for preparation of Trilaciclib intermediates. Further aspects of the present disclosure relate to method for preparation of Trilaciclib, pharmaceutically acceptable salts and derivatives thereof. Still further aspects of the present disclosure are drawn towards use of the Trilaciclib intermediates for the production of Trilaciclib, pharmaceutically acceptable salts or derivatives thereof.