EP4497433A1 — Nano-in-micro encapsulated sirna dry powder and pharmaceutical product containing said dry powder
Assigned to Ludwig Maximilians Universitaet Muenchen LMU · Expires 2025-01-29 · 1y expired
What this patent protects
The invention relates to Nano-in-micro (NIM) encapsulated bioactive siRNA dry powder comprising lipid nanoparticles, the lipid nanoparticles comprising from at least an ionizable cationic lipid, a helper lipid, a stealth lipid, and siRNA, wherein the lipid nanoparticles are encap…
USPTO Abstract
The invention relates to Nano-in-micro (NIM) encapsulated bioactive siRNA dry powder comprising lipid nanoparticles, the lipid nanoparticles comprising from at least an ionizable cationic lipid, a helper lipid, a stealth lipid, and siRNA, wherein the lipid nanoparticles are encapsulated in sugar and/or sugar alcohol, wherein the mass ratio of siRNA to a sugar and/or sugar alcohol is more than 0.10%, especially between 0,90% and 1,30%. The invention also relates to a respective pharmaceutical product containing the dry powder in a sealed volume.
Drugs covered by this patent
- Onpattro (PATISIRAN SODIUM) · Alnylam Pharmaceuticals
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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