EP4355734A1 — Novel manufacturing method of daprodustat and precursors thereof
Assigned to GlaxoSmithKline Intellectual Property No 2 Ltd · Expires 2024-04-24 · 2y expired
What this patent protects
The present disclosure relates to a manufacturing process for daprodustat in which the level of an acyl impurity of Formula (II) is kept below 0.15% w/w in isolated daprodustat drug substance. Immediate release formulations of daprodustat containing a composition of daprodustat i…
USPTO Abstract
The present disclosure relates to a manufacturing process for daprodustat in which the level of an acyl impurity of Formula (II) is kept below 0.15% w/w in isolated daprodustat drug substance. Immediate release formulations of daprodustat containing a composition of daprodustat in which the level of the acyl impurity of Formula (II) is kept below 0.15% w/w relative to daprodustat drug substance are also disclosed. Medical uses of the immediate release formulation and dosage regimens are disclosed.
Drugs covered by this patent
- Jesduvroq (DAPRODUSTAT) · GSK
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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