EP4234532A1 — Trientine tetrahydrochloride and a method of preparation and a pharmaceutical composition thereof
Assigned to Yu Jet Co Ltd · Expires 2023-08-30 · 3y expired
What this patent protects
A method of preparation of trientine tetrahydrochloride crystals in which an anti-solvent at a feeding temperature is added into a trientine tetrahydrochloride solution and stirred for crystallization wherein the feeding temperature ranges from 50°C to 75°C and the anti-solvent i…
USPTO Abstract
A method of preparation of trientine tetrahydrochloride crystals in which an anti-solvent at a feeding temperature is added into a trientine tetrahydrochloride solution and stirred for crystallization wherein the feeding temperature ranges from 50°C to 75°C and the anti-solvent is an alcohol solvent. A novel trientine tetrahydrochloride featuring XRPD peaks detected at 21.9, 24.8, 25.2, 28.0 and 35.6±0.1° 20 for stable storage of a pharmaceutical composition manufactured with the trientine tetrahydrochloride.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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