EP4043018A1 — Composition and method for reducing oxalate levels in patients receiving maintenance dialysis
Assigned to Charite Universitaetsmedizin Berlin · Expires 2022-08-17 · 4y expired
What this patent protects
The invention relates to a composition comprising Lumasiran and/or Nedosiran for use in the treatment or prevention of an oxalate-related disorder in a patient receiving dialysis treatment who does not suffer from Primary Hyperoxaluria 1-3 (PH), preferably a cardiovascular diseas…
USPTO Abstract
The invention relates to a composition comprising Lumasiran and/or Nedosiran for use in the treatment or prevention of an oxalate-related disorder in a patient receiving dialysis treatment who does not suffer from Primary Hyperoxaluria 1-3 (PH), preferably a cardiovascular disease. In further aspects of the invention, the composition comprising Lumasiran and Nedosiran diminishes or blocks hepatic oxalate production in non-PH dialysis receiving patients to prevent or treat cardiovascular events, sudden cardiac death, congestive heart failure, and excess mortality in said patients. The invention further relates to administration, a method for preparing the composition comprising Lumasiran and/or Nedosiran and a kit comprising Lumasiran and/or Nedosiran and instructions for its use.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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