EP4025191A1 — Pharmaceutical compositions of abiraterone acetate
Assigned to Zentiva KS · Expires 2022-07-13 · 4y expired
What this patent protects
The invention provides immediate release pharmaceutical compositions comprising amorphous or predominantly amorphous abiraterone acetate or a salt of abiraterone acetate with a higher solubility and bioavailability, compared to the original dosage form comprising crystalline abir…
USPTO Abstract
The invention provides immediate release pharmaceutical compositions comprising amorphous or predominantly amorphous abiraterone acetate or a salt of abiraterone acetate with a higher solubility and bioavailability, compared to the original dosage form comprising crystalline abiraterone acetate. Improvement in solubility was demonstrated in an in-vitro experiment and in-vivo improvement in bioavailability was demonstrated in rat models and human volunteers.
Drugs covered by this patent
- Nubeqa (darolutamide) · Bayer
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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