EP3834827A1 — N-[5-(3,5-difluorobenzyl)-1h-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-2h-pyran-4-ylamino) benzamide for treating patients with ros1,ntrk1, ntrk2 and ntrk3 mutant cancer cells
Assigned to Nerviano Medical Sciences SRL · Expires 2021-06-16 · 5y expired
What this patent protects
Substituted indazole derivatives of formula (I) or formula 2.(I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be usef…
USPTO Abstract
Substituted indazole derivatives of formula (I) or formula 2.(I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer.
Drugs covered by this patent
- Rozlytrek (entrectinib) · Roche
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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