EP3572071A1 — Lyophilized liposomes
Assigned to Jazz Pharmaceuticals Research LLC · Expires 2019-11-27 · 6y expired
What this patent protects
A lyophilized gel-phase liposomal composition is provided which comprises more than one therapeutic and/or diagnostic agent, substantially no internal cryoprotectant, gel-phase liposomes with gel-to-liquid crystalline transition temperatures (Tc) that are at least 25°C, wherein t…
USPTO Abstract
A lyophilized gel-phase liposomal composition is provided which comprises more than one therapeutic and/or diagnostic agent, substantially no internal cryoprotectant, gel-phase liposomes with gel-to-liquid crystalline transition temperatures (Tc) that are at least 25°C, wherein the liposomes are 20 mol% or less cholesterol liposomes that are stabilized with at least 1% of a phosphatidylglycerol (PG) and/or a phosphoinositol (PI), and cryoprotectant external to said liposomes. The lyophilized gel-phase liposomal composition and said composition reconstituted in a suitable pharmaceutical carrier are provided for use in therapy.
Drugs covered by this patent
- Cytarabine (Cytarabine) · Nippon Shinyaku Co., Ltd.
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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