EP3394057A1 — SYNTHETIC METHODS FOR PREPARATION OF (S)-(2R,3R,11BR)-3-ISOBUTYL-9,10-DIMETHOXY-2,3,4,6,7,11B-HEXAHYDRO-1H-PYRIDO[2,1,-A]lSOQUINOLIN-2-YL 2-AMINO-3-METHYLBUTANOATE DI(4-METHYLBENZENESULFONATE)
Assigned to Neurocrine Biosciences Inc · Expires 2018-10-31 · 8y expired
What this patent protects
Provided herein are processes for the preparation of ( S )-(2 R ,3 R , 11b R )-3-isobutyl-9,10-dimethoxy-2,3,4,6,7, 11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3- methylbutanoate di(4-methylbenzenesulfonate), or a solvate, hydrate, or polymorph thereof.
USPTO Abstract
Provided herein are processes for the preparation of ( S )-(2 R ,3 R , 11b R )-3-isobutyl-9,10-dimethoxy-2,3,4,6,7, 11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3- methylbutanoate di(4-methylbenzenesulfonate), or a solvate, hydrate, or polymorph thereof.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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