EP Patent

EP3328867A1 — Crystalline form of lorlatinib free base

Assigned to Pfizer Inc · Expires 2018-06-06 · 8y expired

What this patent protects

This invention relates to acrystalline form of (10 R )-7-amino-12-fluoro-2,10,16-trimethyl- 5-oxo-10,15,16,17-tetrahydro-2 H -8,4-(metheno)pyrazolo[4,3- h ][2,5,11]benzoxadiazacyclo- tetradecine-3-carbonitrile (lorlatinib) free base (Form 7). This invention also relates to pharma…

USPTO Abstract

This invention relates to acrystalline form of (10 R )-7-amino-12-fluoro-2,10,16-trimethyl- 5-oxo-10,15,16,17-tetrahydro-2 H -8,4-(metheno)pyrazolo[4,3- h ][2,5,11]benzoxadiazacyclo- tetradecine-3-carbonitrile (lorlatinib) free base (Form 7). This invention also relates to pharmaceutical compositions comprising Form 7, and to methods of using Form 7 and such compositions in the treatment of abnormal cell growth, such as cancer, in a mammal.

Drugs covered by this patent

Patent Metadata

Patent number
EP3328867A1
Jurisdiction
EP
Classification
—
Expires
2018-06-06
Drug substance claim
No
Drug product claim
No
Assignee
Pfizer Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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