EP3209317A1 — Method of treating patients with hepatorenal syndrome type 1
Assigned to Mallinckrodt Pharmaceuticals Ireland Ltd · Expires 2017-08-30 · 9y expired
What this patent protects
The principles and embodiments of the present disclosure relate to methods for using terlipressin to treat a patient having impaired renal function associated with liver disease. A patient identified as suffering from HRS-1 is tested to determine if the patient meets at least two…
USPTO Abstract
The principles and embodiments of the present disclosure relate to methods for using terlipressin to treat a patient having impaired renal function associated with liver disease. A patient identified as suffering from HRS-1 is tested to determine if the patient meets at least two out of three criteria, wherein the three criteria include a WBC <4 or >12 cells/µL; HR >90 bpm; and any one of HCO3 <21 mmol/L or PaCO2 <32 mmHg or > 20 breaths per minute. If the patient meets at least two of the criteria, he or she is administered terlipressin in an amount effective to produce a reduction in serum creatinine of at least 1.0 mg/dL.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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