EP2974729A1 — Quinoline derivatives for use in the treatment of inflammatory diseases

USPTO Abstract

The present invention relates to a compound of formula (I) wherein: means an aromatic ring wherein V is C or N and when V is N; Q is N or O, provided that R" does not exist when Q is O; R' independently represent a hydrogen atom or a group chosen among a (C 1 -C 3 )alkyl group, a halogen atom, a hydroxyl group, a-COOR 1 group, a -NO 2 group, a -NR 1 R 2 group, a morpholinyl or a morpholino group, a N-methylpiperazinyl group, a (C 1 -C 3 )fluoroalkyl group, a (C 1 -C 4 )alkoxy group and a -CN group, and can further be a group chosen among: or anyone of its pharmaceutically acceptable salt, for use in the treatment and/or prevention of an inflammatory disease. The invention further relates to some new compounds and to the pharmaceutical composition containing them. It further relates to screening methods.