EP Patent

EP2882706A1 — Amine-containing lipidoids and uses thereof

Assigned to Massachusetts Institute of Technology · Expires 2015-06-17 · 11y expired

What this patent protects

Provided herein are lipidoids that may be prepared from the conjugate addition of alkylamines to acrylates. In some embodiments, provided lipidoids are biodegradable and may be used in a variety of drug delivery systems. Given the amino moiety of the lipidoids, they are well-suit…

USPTO Abstract

Provided herein are lipidoids that may be prepared from the conjugate addition of alkylamines to acrylates. In some embodiments, provided lipidoids are biodegradable and may be used in a variety of drug delivery systems. Given the amino moiety of the lipidoids, they are well-suited for the delivery of polynucleotides, in addition to other agents. Nanoparticles containing the inventive lipidoids and polynucleotides have been prepared and have been shown to be effective in delivering siRNA.

Drugs covered by this patent

Patent Metadata

Patent number
EP2882706A1
Jurisdiction
EP
Classification
—
Expires
2015-06-17
Drug substance claim
No
Drug product claim
No
Assignee
Massachusetts Institute of Technology
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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